Anti-WAS Polyclonal Antibody (HW679014)

Name: Anti-WAS Polyclonal Antibody
Brand: abinScience
SKU: HW679014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW679014

설명

Anti-WAS Polyclonal Antibody (HW679014) is a rabbit polyclonal antibody detecting WAS in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human WAS (Gly40-Glu131).

타겟

WASp, WAS, Wiskott-Aldrich syndrome protein, IMD2

정제

Purified by antigen affinity column.

등록번호

P42768

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Actin nucleation-promoting factor WAS is a ~52 kDa protein. Effector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. In addition to its role in the cytoplasmic cytoskeleton, also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.

1. Cory, GO. et al. (2002) The Journal of biological chemistry 277, 45115-21. PMID: 12235133

2. Cory, GO. et al. (2003) Molecular cell 11, 1229-39. PMID: 12769847

3. Chereau, D. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 16644-9. PMID: 16275905

4. Symons, M. et al. (1996) Cell 84, 723-34. PMID: 8625410

5. Ramesh, N. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 14671-6. PMID: 9405671

6. Cheng, HC. et al. (2008) Nature 454, 1009-13. PMID: 18650809

7. Taylor, MD. et al. (2010) Science translational medicine 2, 37ra44. PMID: 20574068

8. Schrank, BR. et al. (2018) Nature 559, 61-66. PMID: 29925947

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-WAS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-WAS Polyclonal Antibody (HW679014)

개요

이미지

참고 문헌

데이터시트

SDS

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