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| 카탈로그 번호 | HV550014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-WDFY1 Polyclonal Antibody (HV550014) is a rabbit polyclonal antibody detecting WDFY1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human WDFY1 (Met1-His410). | ||||||||
| 타겟 | FENS-1, Zinc finger FYVE domain-containing protein 17, WD40- and FYVE domain-containing protein 1, FYVE domain-containing protein localized to endosomes 1, KIAA1435, ZFYVE17, WDFY1, FENS1, WD repeat and FYVE domain-containing protein 1, Phosphoinositide-binding protein 1, WDF1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8IWB7 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | WD repeat and FYVE domain-containing protein 1 (WDFY1) is a ~46 kDa protein. Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. 1. Hu, YH. et al. (2015) EMBO reports 16, 447-55. PMID: 25736436 | ||||||||
| 참고사항 | For research use only. |
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