Anti-WNT5A Polyclonal Antibody (HW294014)

Name: Anti-WNT5A Polyclonal Antibody
Brand: abinScience
SKU: HW294014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW294014

설명

Anti-WNT5A Polyclonal Antibody (HW294014) is a rabbit polyclonal antibody detecting WNT5A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Alopias vulpinus, and Ambystoma mexicanum.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human WNT5A (Ile62-Lys380).

타겟

Protein Wnt-5a, WNT5A

정제

Purified by antigen affinity column.

등록번호

P41221

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein Wnt-5a (WNT5A) is a ~42 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation.

1. Kremenevskaja, N. et al. (2005) Oncogene 24, 2144-54. PMID: 15735754

2. Dissanayake, SK. et al. (2007) The Journal of biological chemistry 282, 17259-71. PMID: 17426020

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-WNT5A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-WNT5A Polyclonal Antibody (HW294014)

개요

이미지

참고 문헌

데이터시트

SDS

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