Anti-YTHDF2 Polyclonal Antibody (MP332014)

Name: Anti-YTHDF2 Polyclonal Antibody
Brand: abinScience
SKU: MP332014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MP332014

설명

Anti-YTHDF2 Polyclonal Antibody (MP332014) is a rabbit polyclonal antibody detecting YTH domain-containing family protein 2; Ythdf2 in ELISA, IHC, WB. Suitable for Bovine, Mouse, Zebrafish, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant mouse YTHDF2 (Pro385-Lys579).

타겟

YTH domain-containing family protein 2; Ythdf2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

E7F1H9, Q7Z739, Q9Y5A9, Q8BYK6, Q9BYJ9, Q0VCZ3, Q91YT7, P59326

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

YTH domain-containing family protein 2 (YTHDF2) is a ~66 kDa protein. Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability by promoting degradation of m6A-containing mRNAs. The YTHDF paralogs (ythdf1, ythdf2 and ythdf3) share m6A-containing mRNAs targets and act redundantly to mediate mRNA degradation and cellular differentiation. Plays a key role in maternal-to-zygotic transition during early embryonic development, the process during which maternally inherited mRNAs are degraded: acts by binding m6A-containing maternal mRNAs and promoting their degradation.

1. Zhao, BS. et al. (2017) Nature 542, 475-478. PMID: 28192787

2. Zhang, C. et al. (2017) Nature 549, 273-276. PMID: 28869969

참고사항

For research use only

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참고 문헌

데이터시트

Anti-YTHDF2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-YTHDF2 Polyclonal Antibody (MP332014)

개요

이미지

참고 문헌

데이터시트

SDS