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| 카탈로그 번호 | VK661014 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-ZEBOV VP35 Polyclonal Antibody (VK661014) is a rabbit polyclonal antibody detecting VP35 in ELISA, IHC, WB. Suitable for Reston ebolavirus, Zaire ebolavirus, and Sudan ebolavirus.
Highlights
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| 종 반응성 | Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| 응용 분야 | ELISA, IHC, WB | ||||
| 숙주 종 | Rabbit | ||||
| 클론성 | Polyclonal | ||||
| 이소타입 | IgG | ||||
| 면역원 | E. coli - derived recombinant ZEBOV VP35 (Gly215-Ile340). | ||||
| 타겟 | Polymerase cofactor VP35, Ebola VP35, eVP35, VP35 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 정제 | Purified by antigen affinity column. | ||||
| 등록번호 | Q8JPY0, Q5XX07, Q05127, Q6V1Q9, Q91DE0 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Polymerase cofactor VP35 is a ~36 kDa protein. Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes. Part of the external layer of the nucleocapsid, likely tethering the nucleocapsid to the matrix and membrane. Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1. 1. Kimberlin, CR. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 314-9. PMID: 20018665 | ||||
| 참고사항 | For research use only |
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