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| 카탈로그 번호 | MB651209 |
|---|---|
| 설명 |
InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651209) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse.
Highlights
|
| 종 반응성 | Mouse |
| 응용 분야 | in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2b, kappa |
| 클론 ID | 9D9 |
| 타겟 | CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| 내독소 수준 | < 1 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P09793 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). |
| 참고사항 | For research use only. |
| Isotype Control | Mouse IgG2b, kappa Recombinant Isotype Control Antibody (MPC-11) (MF974207) |
SDS-PAGE for InVivo Plus Anti-Mouse CD152/CTLA4 Antibody (9D9)
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