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| 카탈로그 번호 | MF815109 |
|---|---|
| 설명 |
InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43) [2.43] (MF815109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization. Suitable for Mouse.
Highlights
|
| 종 반응성 | Mouse |
| 응용 분야 | FCM, in vivo CD8+ T cell depletion, Western blot, Neutralization |
| 숙주 종 | Rat |
| 클론성 | Monoclonal |
| 이소타입 | lgG2b |
| 클론 ID | 2.43 |
| 타겟 | CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2 |
| 내독소 수준 | < 1 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P01731 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| 참고사항 | For research use only. |
| Isotype Control | Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107) |
SDS-PAGE for InVivo Plus Anti-Mouse CD8a/Lyt2 Antibody (2.43)
Detects CD8a/Lyt2 (Catalog No. MF815011) in indirect ELISAs.
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