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| 카탈로그 번호 | VK646020 | ||||
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| 설명 |
InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260) [Iv0260] (VK646020) is a human monoclonal antibody detecting Envelopment polyprotein in ELISA, Neutralization. Suitable for Seoul virus (SEOV) and Andes virus (ANDV).
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| 종 반응성 | Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV), Orthohantavirus puumalaense (Puumala virus) (PUUV), Dobrava-Belgrade virus (DOBV), Seoul virus (SEOV), Andes virus (Andes orthohantavirus), Sin Nombre virus (SNV) | ||||
| 응용 분야 | ELISA, Neutralization | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1 | ||||
| 클론 ID | Iv0260 | ||||
| 타겟 | Envelopment polyprotein, M polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 관련 제품 | pH 7.4 Dilution Buffer | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q89905 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif. | ||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260)
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