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| 카탈로그 번호 | VK802010 |
|---|---|
| 설명 |
InVivoMAb Anti-HAV Capsid protein VP2 Antibody (R10) [R10] (VK802010) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
|
| 종 반응성 | Hepatitis A virus (HAV) |
| 응용 분야 | ELISA, Neutralization |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1 |
| 클론 ID | R10 |
| 타겟 | Genome polyprotein, Capsid protein VP2, P1B, Virion protein 2 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P08617 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Genome polyprotein (Capsid protein VP2) is a ~251 kDa protein. Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell. 1. Wang, X. et al. (2015) Nature 517, 85-88. PMID: 25327248 2. Wang, X. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 770-775. PMID: 28074040 3. Silberstein, E. et al. (2001) Journal of virology 75, 717-25. PMID: 11134285 4. Costafreda, MI. et al. (2018) Journal of virology 92. PMID: 29437974 5. Feigelstock, D. et al. (1998) Journal of virology 72, 6621-8. PMID: 9658108 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-HAV Capsid protein VP2 Antibody (R10)
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