InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12) (MV029010)

Name: InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12)
Brand: abinScience
SKU: MV029010
Price: 370 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

100ug
1mg

수량:

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MV029010

설명

InVivoMab Anti-Mouse CD366/HAVCR2/TIM-3 Antibody (B8.2C12) [B8.2C12] (MV029010) is a rat monoclonal antibody detecting CD366 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

숙주 종

Rat

클론성

Monoclonal

이소타입

IgG1, kappa

클론 ID

B8.2C12

타겟

CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3

내독소 수준

< 1 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

Q3KP82

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Hepatitis A virus cellular receptor 2 homolog (CD366/HAVCR2) is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006

4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895

5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785

6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702

7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532

8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673

9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762

참고사항

For research use only.

이미지

참고 문헌

데이터시트

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12) (MV029010)

개요

이미지

참고 문헌

데이터시트

SDS

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