

| 카탈로그 번호 | MV721010 |
|---|---|
| 설명 |
InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) [Iv0257] (MV721010) is a mouse monoclonal antibody detecting V-set domain containing T-cell activation inhibitor 1 in ELISA, FCM, Neutralization. Suitable for Mouse.
Highlights
|
| 종 반응성 | Mouse |
| 응용 분야 | ELISA, FCM, Neutralization |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a, kappa |
| 클론 ID | Iv0257 |
| 테스트된 응용 분야 | FCM |
| 타겟 | V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q7TSP5 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | V-set domain containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |

Flow-cytometry using anti-human VTCN1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human VTCN1 monoclonal antibody (Catalog: MV721010) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.


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