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| 카탈로그 번호 | HD924012 |
|---|---|
| 설명 |
Recombinant Human ABCG5 Protein, N-His (HD924012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9H222 |
| 단백질 길이 | His36-Lys349 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ABCG5, ATP-binding cassette sub-family G member 5, EC:7.6.2.-, Sterolin-1 |
| 배경 | ATP-binding cassette sub-family G member 5 is a ~72 kDa protein. ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. 1. Lee, JY. et al. (2016) Nature 533, 561-4. PMID: 27144356 2. Berge, KE. et al. (2000) Science (New York, N.Y.) 290, 1771-5. PMID: 11099417 3. Lee, MH. et al. (2001) Nature genetics 27, 79-83. PMID: 11138003 4. Graf, GA. et al. (2004) The Journal of biological chemistry 279, 24881-8. PMID: 15054092 5. Wang, Z. et al. (2006) Biochemistry 45, 9929-39. PMID: 16893193 6. Johnson, BJ. et al. (2010) Biochemistry 49, 3403-11. PMID: 20210363 |
| 참고사항 | For research use only |
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