

| 카탈로그 번호 | HT100011 |
|---|---|
| 설명 |
Recombinant Human AGRP Protein, C-Fc (HT100011) expressed in Mammalian Cells, spanning Met1-Thr132. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | Mammalian cells |
| 등록번호 | O00253 |
| 단백질 길이 | Met1-Thr132 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 40.84 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | AGRP, AGRT, ART, Agouti-related protein |
| 배경 | Agouti-related protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism. 1. Bolin, KA. et al. (1999) FEBS letters 451, 125-31. PMID: 10371151 2. Nijenhuis, WA. et al. (2001) Molecular endocrinology (Baltimore, Md.) 15, 164-71. PMID: 11145747 3. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920 4. Yang, YK. et al. (1999) Molecular endocrinology (Baltimore, Md.) 13, 148-55. PMID: 9892020 5. de Rijke, CE. et al. (2005) Biochemical pharmacology 70, 308-16. PMID: 15927146 6. Breit, A. et al. (2006) The Journal of biological chemistry 281, 37447-56. PMID: 17041250 |
| 참고사항 | For research use only |
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