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| 카탈로그 번호 | HC918012 |
|---|---|
| 설명 |
Recombinant Human AK4/AK3L1 Protein, N-His (HC918012) expressed in E. coli, spanning Met1-Tyr223. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P27144 |
| 단백질 길이 | Met1-Tyr223 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 27.43 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | AK3, AK3L1, AK4, Adenylate kinase 3-like, Adenylate kinase 4, mitochondrial, EC:2.7.4.4, EC:2.7.4.6, GTP:AMP phosphotransferase AK4 |
| 배경 | Adenylate kinase 4, mitochondrial is a ~25 kDa protein. Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. Phosphorylates only AMP when using GTP as phosphate donor. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. 1. Liu, R. et al. (2009) Biochemical and biophysical research communications 379, 92-7. PMID: 19073142 2. Panayiotou, C. et al. (2010) The international journal of biochemistry & cell biology 42, 62-9. PMID: 19766732 3. Amiri, M. et al. (2013) The international journal of biochemistry & cell biology 45, 925-31. PMID: 23416111 4. Lanning, NJ. et al. (2014) Cell reports 7, 907-17. PMID: 24767988 |
| 참고사항 | For research use only |
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