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Human ATL2 Recombinant Protein (N-His) (HD526012)

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사양:
  • 50ug
  • 100ug
  • 1mg
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  • 개요

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  • 데이터시트

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개요
카탈로그 번호HD526012
설명
Recombinant Human ATL2 Protein, N-His (HD526012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템E. coli
등록번호Q8NHH9
단백질 길이Val61-Gly365
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Homo sapiens (Human)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름ADP-ribosylation factor-like protein 6-interacting protein 2, ARL6IP2, ATL-2, ATL2, Atlastin-2, EC:3.6.5.-
배경

Atlastin-2 is a ~66 kDa protein. Atlastin-2 (ATL2) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-2 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi).

1. Rismanchi, N. et al. (2008) Human molecular genetics 17, 1591-604. PMID: 18270207
2. Hu, J. et al. (2009) Cell 138, 549-61. PMID: 19665976
3. Morin-Leisk, J. et al. (2011) The Journal of cell biology 195, 605-15. PMID: 22065636
4. Wang, S. et al. (2016) eLife 5. PMID: 27619977
5. Crosby, D. et al. (2022) The Journal of cell biology 221. PMID: 34817557
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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