Human LILRB1/CD85j/ILT2 Recombinant Protein (C-Fc) (HV631021)

Name: Human LILRB1/CD85j/ILT2 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HV631021
Price: 298 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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50ug
100ug
1mg

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HV631021
설명	Recombinant Human CD85j/LILRB1 Protein, C-Fc (HV631021) expressed in Mammalian Cells, spanning Met1-His458. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	Mammalian cells
등록번호	Q8NHL6
단백질 길이	Met1-His458
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	76.02 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	CD85 antigen-like family member J, CD85j, ILT-2, ILT2, Immunoglobulin-like transcript 2, LILRB1, LIR-1, LIR1, Leukocyte immunoglobulin-like receptor 1, Leukocyte immunoglobulin-like receptor subfamily B member 1, MIR-7, MIR7, Monocyte/macrophage immunoglobulin-like receptor 7
배경	Leukocyte immunoglobulin-like receptor subfamily B member 1 is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
참고사항	For research use only