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| 카탈로그 번호 | HD802012 |
|---|---|
| 설명 |
Recombinant Human CHD6 Protein, N-His (HD802012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q8TD26 |
| 단백질 길이 | Tyr455-Arg682 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ATP-dependent chromatin remodeler CHD6, CHD-6, CHD5, CHD6, Chromo domain-containing protein 6, EC:3.6.4.-, KIAA1335, RIGB, Radiation-induced gene B protein |
| 배경 | ATP-dependent chromatin remodeler CHD6 is a ~305 kDa protein. ATP-dependent chromatin-remodeling factor. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin; nucleosome disruption requires ATP. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. 1. Lutz, T. et al. (2006) FEBS letters 580, 5851-7. PMID: 17027977 2. Manning, BJ. et al. (2017) The Journal of biological chemistry 292, 11927-11936. PMID: 28533432 |
| 참고사항 | For research use only |
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