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| 카탈로그 번호 | HC982012 |
|---|---|
| 설명 |
Recombinant Human CRYAA Protein, N-His (HC982012) expressed in E. coli, spanning Met1-Ser173. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P02489 |
| 단백질 길이 | Met1-Ser173 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 22.07 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Alpha-crystallin A chain, Alpha-crystallin A(1-162), Alpha-crystallin A(1-168), Alpha-crystallin A(1-172), CRYA1, CRYAA, HSPB4, Heat shock protein beta-4, Heat shock protein family B member 4, HspB4 |
| 배경 | Alpha-crystallin A chain is a ~19 kDa protein. Contributes to the transparency and refractive index of the lens. In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. 1. Richter, L. et al. (2008) American journal of medical genetics. Part A 146A, 833-42. PMID: 18302245 2. Murugesan, R. et al. (2007) Molecular vision 13, 2301-9. PMID: 18199971 3. Bhagyalaxmi, SG. et al. (2009) Biochimica et biophysica acta 1792, 974-81. PMID: 19595763 4. Nagaraj, RH. et al. (2012) Biochimica et biophysica acta 1822, 120-9. PMID: 22120592 5. Kaiser, CJO. et al. (2019) Nature structural & molecular biology 26, 1141-1150. PMID: 31792453 6. Chaves, JM. et al. (2017) Biochemical and biophysical research communications 494, 402-408. PMID: 28935373 |
| 참고사항 | For research use only |
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