

| 카탈로그 번호 | HD836012 |
|---|---|
| 설명 |
Recombinant Human GTF2B Protein, N-His (HD836012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q00403 |
| 단백질 길이 | Ser108-Leu316 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | EC:2.3.1.48, GTF2B, General transcription factor TFIIB, S300-II, TF2B, TFIIB, Transcription initiation factor IIB |
| 배경 | Transcription initiation factor IIB is a ~34 kDa protein. General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter-specific regions. 1. Choi, CH. et al. (2003) Nature 424, 965-9. PMID: 12931194 2. Ing, NH. et al. (1992) The Journal of biological chemistry 267, 17617-23. PMID: 1517211 3. Ha, I. et al. (1991) Nature 352, 689-95. PMID: 1876184 4. Malik, S. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 9553-7. PMID: 1946368 5. He, Y. et al. (2016) Nature 533, 359-65. PMID: 27193682 6. Reinberg, D. et al. (1987) The Journal of biological chemistry 262, 3310-21. PMID: 3029109 7. Reinberg, D. et al. (1987) The Journal of biological chemistry 262, 3322-30. PMID: 3818643 8. Zawel, L. et al. (1995) Genes & development 9, 1479-90. PMID: 7601352 9. Malik, S. et al. (1993) Molecular and cellular biology 13, 6253-9. PMID: 8413225 10. Hisatake, K. et al. (1993) Nature 363, 744-7. PMID: 8515820 |
| 참고사항 | For research use only |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206

中文
English
한국어
日本語
Español
Français
Русский