

| 카탈로그 번호 | HD167012 |
|---|---|
| 설명 |
Recombinant Human HHEX Protein, N-His-KSI (HD167012) expressed in E. coli, spanning Gln2-Gly270. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q03014 |
| 단백질 길이 | Gln2-Gly270 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 45.65 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | HEX, HHEX, Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH, PRH, PRHX, Proline-rich homeodomain protein |
| 배경 | Hematopoietically-expressed homeobox protein HHEX is a ~30 kDa protein. Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. 1. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982 2. Topisirovic, I. et al. (2003) The EMBO journal 22, 689-703. PMID: 12554669 3. Bedford, FK. et al. (1993) Nucleic acids research 21, 1245-9. PMID: 8096636 |
| 참고사항 | For research use only |
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