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| 카탈로그 번호 | HD306012 |
|---|---|
| 설명 |
Recombinant Human IER5 Protein, N-His-KSI (HD306012) expressed in E. coli, spanning Glu2-Pro166. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q5VY09 |
| 단백질 길이 | Glu2-Pro166 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 32.95 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | IER5, Immediate early response gene 5 protein |
| 배경 | Immediate early response gene 5 protein is a ~33 kDa protein. Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner. Mediates negative transcriptional regulation of CDC25B expression. Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A. Involved in the regulation of cell proliferation and resistance to thermal stress. 1. Nakamura, S. et al. (2011) PloS one 6, e28011. PMID: 22132193 2. Ishikawa, Y. et al. (2015) The FEBS journal 282, 332-40. PMID: 25355627 3. Ishikawa, Y. et al. (2015) FEBS letters 589, 1150-5. PMID: 25816751 4. Kawabata, S. et al. (2015) FEBS letters 589, 3679-85. PMID: 26496226 |
| 참고사항 | For research use only |
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