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| 카탈로그 번호 | HC472012 |
|---|---|
| 설명 |
Recombinant Human IL24 Protein, N-His (HC472012) expressed in E. coli, spanning Gln52-Leu206. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q13007 |
| 단백질 길이 | Gln52-Leu206 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 20.46 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | MDA7, MDA-7, ST16, IL-24, Melanoma differentiation-associated gene 7 protein, Suppression of tumorigenicity 16 protein, IL24, Interleukin-24 |
| 배경 | Interleukin-24 (IL24) is a ~23 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. 1. Jin, SH. et al. (2014) Toxicology and applied pharmacology 280, 199-206. PMID: 25168428 2. Seong, RK. et al. (2016) Journal of microbiology (Seoul, Korea) 54, 695-700. PMID: 27687232 3. Wang, M. et al. (2002) The Journal of biological chemistry 277, 7341-7. PMID: 11706020 4. Lubkowski, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 201, 2082-2093. PMID: 30111632 |
| 참고사항 | For research use only. |
SDS-PAGE for Recombinant Human IL24 Protein, N-His
Detected by Anti-Mouse IL24 antibody (SAA2230) (Catalog No: MC472013) in indirect ELISA
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
