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| 카탈로그 번호 | HW529012 |
|---|---|
| 설명 |
Recombinant Human KCNC1 Protein, N-His (HW529012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P48547 |
| 단백질 길이 | Met1-Arg190 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | KCNC1, NGK2, Potassium voltage-gated channel subfamily C member 1, Voltage-gated potassium channel KCNC1, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4 |
| 배경 | Voltage-gated potassium channel KCNC1 is a ~57 kDa protein. Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient. The mechanism is time-dependent and inactivation is slow. Plays an important role in the rapid repolarization of fast-firing brain neurons. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons. 1. Muona, M. et al. (2015) Nature genetics 47, 39-46. PMID: 25401298 2. Chi, G. et al. (2022) Nature communications 13, 4087. PMID: 35840580 |
| 참고사항 | For research use only |
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