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| 카탈로그 번호 | HP896022 |
|---|---|
| 설명 |
Recombinant Human KCNE4 Protein, N-GST & C-His (HP896022) expressed in E. coli, spanning His2-Glu86. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q8WWG9 |
| 단백질 길이 | His2-Glu86 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 36.84 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | KCNE4, MiRP3, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3, Potassium voltage-gated channel subfamily E member 4 |
| 배경 | Potassium voltage-gated channel subfamily E member 4 is a ~23 kDa protein. Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. 1. Grunnet, M. et al. (2002) The Journal of physiology 542, 119-30. PMID: 12096056 2. Vanoye, CG. et al. (2009) The Journal of general physiology 134, 207-17. PMID: 19687231 3. Roura-Ferrer, M. et al. (2010) Journal of cellular physiology 225, 692-700. PMID: 20533308 4. Abbott, GW. (2016) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30, 2959-69. PMID: 27162025 |
| 참고사항 | For research use only |
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