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| 카탈로그 번호 | HD854012 |
|---|---|
| 설명 |
Recombinant Human KIF1A Protein, N-His (HD854012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q12756 |
| 단백질 길이 | Met1-Glu362 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ATSV, Axonal transporter of synaptic vesicles, C2orf20, EC:5.6.1.3, KIF1A, Kinesin-like protein KIF1A, Microtubule-based motor KIF1A, Unc-104- and KIF1A-related protein, hUnc-104 |
| 배경 | Kinesin-like protein KIF1A is a ~191 kDa protein. Kinesin motor with a plus-end-directed microtubule motor activity. It is required for anterograde axonal transport of synaptic vesicle precursors. Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites. 1. Boyle, L. et al. (2021) HGG advances 2. PMID: 33880452 |
| 참고사항 | For research use only |
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