中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HD221012 |
|---|---|
| 설명 |
Recombinant Human LPIN1 Protein, N-His (HD221012) expressed in E. coli, spanning Asn621-Pro851. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q14693 |
| 단백질 길이 | Asn621-Pro851 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 28.53 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | EC:3.1.3.4, KIAA0188, LPIN1, Lipin-1, Phosphatidate phosphatase LPIN1 |
| 배경 | Phosphatidate phosphatase LPIN1 is a ~98 kDa protein. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels. Is involved in adipocyte differentiation. Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. 1. Han, GS. et al. (2010) The Journal of biological chemistry 285, 14628-38. PMID: 20231281 2. Eaton, JM. et al. (2013) The Journal of biological chemistry 288, 9933-9945. PMID: 23426360 3. Li, TY. et al. (2018) Nature communications 9, 1916. PMID: 29765047 4. MacVicar, T. et al. (2019) Nature 575, 361-365. PMID: 31695197 |
| 참고사항 | For research use only |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
