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Human LRIF1 Recombinant Protein (N-His) (HD601012)

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사양:
  • 50ug
  • 100ug
  • 1mg
수량:
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  • 개요

  • 이미지

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  • 데이터시트

  • SDS

개요
카탈로그 번호HD601012
설명
Recombinant Human LRIF1 Protein, N-His (HD601012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템E. coli
등록번호Q5T3J3
단백질 길이His190-Asn311
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Homo sapiens (Human)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름C1orf103, HBiX1, HP1-binding protein enriched in inactive X chromosome protein 1, LRIF1, Ligand-dependent nuclear receptor-interacting factor 1, RIF1, Receptor-interacting factor 1
배경

Ligand-dependent nuclear receptor-interacting factor 1 is a ~84 kDa protein. Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells.

1. Nozawa, RS. et al. (2013) Nature structural & molecular biology 20, 566-73. PMID: 23542155
2. Li, HJ. et al. (2007) Journal of cellular biochemistry 102, 1021-35. PMID: 17455211
3. Hamanaka, K. et al. (2020) Neurology 94, e2441-e2447. PMID: 32467133
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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