Human LTN1 Recombinant Protein (N-His) (HC968012)

Name: Human LTN1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC968012
Price: 211 USD
Availability: InStock

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1mg

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개요

카탈로그 번호	HC968012
설명	Recombinant Human LTN1 Protein, N-His (HC968012) expressed in E. coli, spanning Glu1587-Phe1766. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	O94822
단백질 길이	Glu1587-Phe1766
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	22.96 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	C21orf10, C21orf98, E3 ubiquitin-protein ligase listerin, EC:2.3.2.27, KIAA0714, LTN1, RING finger protein 160, RING-type E3 ubiquitin transferase listerin, RNF160, ZNF294, Zinc finger protein 294
배경	E3 ubiquitin-protein ligase listerin is a ~200 kDa protein. E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Within the RQC complex, LTN1 is recruited to stalled 60S ribosomal subunits by NEMF and mediates ubiquitination of stalled nascent chains. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product. 1. Shao, S. et al. (2013) Molecular cell 50, 637-48. PMID: 23685075 2. Shao, S. et al. (2014) Molecular cell 55, 880-890. PMID: 25132172 3. Shao, S. et al. (2015) Molecular cell 57, 433-44. PMID: 25578875 4. Matsuo, Y. et al. (2017) Nature communications 8, 159. PMID: 28757607
참고사항	For research use only

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Human LTN1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human LTN1 Recombinant Protein (N-His) (HC968012)

개요

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데이터시트

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