Human MOV10 Recombinant Protein (N-His) (HC181012)

Name: Human MOV10 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC181012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	HC181012
설명	Recombinant Human MOV10 Protein, N-His (HC181012) expressed in E. coli, spanning Glu498-Arg733. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q9HCE1
단백질 길이	Glu498-Arg733
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	28.50 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	Armitage homolog, EC:3.6.4.13, Helicase MOV-10, KIAA1631, MOV10, Moloney leukemia virus 10 protein
배경	Helicase MOV-10 is a ~113 kDa protein. 5' to 3' RNA helicase that is involved in a number of cellular roles ranging from mRNA metabolism and translation, modulation of viral infectivity, inhibition of retrotransposition, or regulation of synaptic transmission. Plays an important role in innate antiviral immunity by promoting type I interferon production. Mechanistically, specifically uses IKKepsilon/IKBKE as the mediator kinase for IRF3 activation. Blocks HIV-1 virus replication at a post-entry step. Counteracts HIV-1 Vif-mediated degradation of APOBEC3G through its helicase activity by interfering with the ubiquitin-proteasome pathway. 1. Goodier, JL. et al. (2012) PLoS genetics 8, e1002941. PMID: 23093941 2. Cuevas, RA. et al. (2016) Journal of immunology (Baltimore, Md. : 1950) 196, 3877-86. PMID: 27016603 3. Balinsky, CA. et al. (2017) Journal of virology 91. PMID: 27974568 4. Yang, X. et al. (2022) PLoS pathogens 18, e1010301. PMID: 35157734 5. Wang, X. et al. (2010) The Journal of biological chemistry 285, 14346-55. PMID: 20215113 6. Chen, C. et al. (2017) Retrovirology 14, 56. PMID: 29258557 7. Liu, T. et al. (2019) The Journal of biological chemistry 294, 19804-19813. PMID: 31722967 8. Gregersen, LH. et al. (2014) Molecular cell 54, 573-85. PMID: 24726324 10. Chendrimada, TP. et al. (2007) Nature 447, 823-8. PMID: 17507929
참고사항	For research use only

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Human MOV10 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human MOV10 Recombinant Protein (N-His) (HC181012)

개요

이미지

참고 문헌

데이터시트

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