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| 카탈로그 번호 | HD795012 |
|---|---|
| 설명 |
Recombinant Human NDST2 Protein, N-His (HD795012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P52849 |
| 단백질 길이 | Ser41-Glu597 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2, EC:2.8.2.-, EC:2.8.2.8, EC:3.-.-.-, Glucosaminyl N-deacetylase/N-sulfotransferase 2, HSST2, Heparan sulfate N-deacetylase 2, Heparan sulfate N-sulfotransferase 2, N-HSST 2, N-heparan sulfate sulfotransferase 2, NDST-2, NDST2 |
| 배경 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 is a ~100 kDa protein. Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan. 1. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413 |
| 참고사항 | For research use only |
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