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| 카탈로그 번호 | HC721012 |
|---|---|
| 설명 |
Recombinant Human NUF2 Protein, N-His (HC721012) expressed in E. coli, spanning Met1-Ser171. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9BZD4 |
| 단백질 길이 | Met1-Ser171 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 22.24 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CDCA1, Cell division cycle-associated protein 1, Kinetochore protein Nuf2, NUF2, NUF2R, hNuf2, hNuf2R, hsNuf2 |
| 배경 | Kinetochore protein Nuf2 is a ~54 kDa protein. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. 1. DeLuca, JG. et al. (2002) The Journal of cell biology 159, 549-55. PMID: 12438418 2. DeLuca, JG. et al. (2003) Current biology : CB 13, 2103-9. PMID: 14654001 3. Joseph, J. et al. (2004) Current biology : CB 14, 611-7. PMID: 15062103 4. Stucke, VM. et al. (2004) Chromosoma 113, 1-15. PMID: 15235793 5. Meraldi, P. et al. (2004) Developmental cell 7, 45-60. PMID: 15239953 6. DeLuca, JG. et al. (2005) Molecular biology of the cell 16, 519-31. PMID: 15548592 7. Liu, D. et al. (2007) The Journal of biological chemistry 282, 21415-24. PMID: 17535814 8. Schmidt, JC. et al. (2012) Developmental cell 23, 968-80. PMID: 23085020 |
| 참고사항 | For research use only |
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