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| 카탈로그 번호 | HD147012 |
|---|---|
| 설명 |
Recombinant Human OGDHL Protein, N-His (HD147012) expressed in E. coli, spanning Gln232-Lys564. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9ULD0 |
| 단백질 길이 | Gln232-Lys564 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 40.14 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | 2-oxoglutarate dehydrogenase complex component E1-like, 2-oxoglutarate dehydrogenase-like, mitochondrial, Alpha-ketoglutarate dehydrogenase-like, EC:1.2.4.2, KIAA1290, OGDC-E1-like, OGDHL |
| 배경 | 2-oxoglutarate dehydrogenase-like, mitochondrial is a ~114 kDa protein. 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. 1. Sen, T. et al. (2012) PloS one 7, e48770. PMID: 23152800 2. Liu, Y. et al. (2019) Clinical cancer research : an official journal of the American Association for Cancer Research 25, 5407-5421. PMID: 31175094 |
| 참고사항 | For research use only |
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