Human PARP2 Recombinant Protein (N-GST & C-His) (HV249022)

Name: Human PARP2 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HV249022
Price: 211 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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50ug
100ug
1mg

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개요
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참고 문헌
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SDS

개요

카탈로그 번호	HV249022
설명	Recombinant Human PARP2 Protein, N-GST & C-His (HV249022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q9UGN5
단백질 길이	Ser223-Trp583
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	ADP-ribosyltransferase diphtheria toxin-like 2, ADPRT-2, ADPRT2, ADPRTL2, ARTD2, DNA ADP-ribosyltransferase PARP2, EC:2.4.2.-, EC:2.4.2.30, NAD(+) ADP-ribosyltransferase 2, PARP-2, PARP2, Poly [ADP-ribose] polymerase 2, Poly[ADP-ribose] synthase 2, Protein poly-ADP-ribosyltransferase PARP2, hPARP-2, pADPRT-2
배경	Poly [ADP-ribose] polymerase 2 is a ~66 kDa protein. Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. Mediates glutamate and aspartate ADP-ribosylation of target proteins in absence of HPF1. Following interaction with HPF1, catalyzes serine ADP-ribosylation of target proteins; HPF1 conferring serine specificity by completing the PARP2 active site. 1. Amé, JC. et al. (1999) The Journal of biological chemistry 274, 17860-8. PMID: 10364231 2. Vyas, S. et al. (2014) Nature communications 5, 4426. PMID: 25043379 3. Talhaoui, I. et al. (2016) Nucleic acids research 44, 9279-9295. PMID: 27471034 4. Chen, Q. et al. (2018) Nature communications 9, 3233. PMID: 30104678 5. Suskiewicz, MJ. et al. (2020) Nature 579, 598-602. PMID: 32028527 6. Bilokapic, S. et al. (2020) Nature 585, 609-613. PMID: 32939087 7. Obaji, E. et al. (2021) Nature communications 12, 3479. PMID: 34108479 8. Bacic, L. et al. (2021) eLife 10. PMID: 34486521 9. Mohapatra, J. et al. (2021) eLife 10. PMID: 34874266
참고사항	For research use only

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Human PARP2 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Human PARP2 Recombinant Protein (N-GST & C-His) (HV249022)

개요

이미지

참고 문헌

데이터시트

SDS

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