Human PIAS1 Recombinant Protein (N-His) (HC963012)

Name: Human PIAS1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC963012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	HC963012
설명	Recombinant Human PIAS1 Protein, N-His (HC963012) expressed in E. coli, spanning Gln139-Lys420. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	O75925
단백질 길이	Gln139-Lys420
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	34.15 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	DDXBP1, DEAD/H box-binding protein 1, E3 SUMO-protein ligase PIAS1, E3 SUMO-protein transferase PIAS1, EC:2.3.2.-, GBP, Gu-binding protein, PIAS1, Protein inhibitor of activated STAT protein 1, RNA helicase II-binding protein
배경	E3 SUMO-protein ligase PIAS1 is a ~71 kDa protein. Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Catalyzes sumoylation of various proteins, such as CEBPB, MRE11, MTA1, PTK2, PML and ZNF76. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. 1. Kahyo, T. et al. (2001) Molecular cell 8, 713-8. PMID: 11583632 2. Schmidt, D. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 2872-7. PMID: 11867732 3. Kadaré, G. et al. (2003) The Journal of biological chemistry 278, 47434-40. PMID: 14500712 4. Zheng, G. et al. (2004) The Journal of biological chemistry 279, 42410-21. PMID: 15280358 5. Cong, L. et al. (2011) The Journal of biological chemistry 286, 43793-43808. PMID: 21965678 6. Zhang, T. et al. (2022) Nature communications 13, 5133. PMID: 36050397
참고사항	For research use only

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Human PIAS1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

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Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human PIAS1 Recombinant Protein (N-His) (HC963012)

개요

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