Human PIP4K2A Recombinant Protein (N-His) (HD637012)

Name: Human PIP4K2A Recombinant Protein (N-His)
Brand: abinScience
SKU: HD637012
Price: 211 USD
Availability: InStock

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1mg

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개요

카탈로그 번호	HD637012
설명	Recombinant Human PIP4K2A Protein, N-His (HD637012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	P48426
단백질 길이	Ser34-Thr406
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, EC:2.7.1.149, PI(5)P 4-kinase type II alpha, PI5P4KA, PI5P4Kalpha, PIP4K2A, PIP4KII-alpha, PIP5K2, PIP5K2A, PIP5KIII, Phosphatidylinositol 5-Phosphate 4-Kinase, Phosphatidylinositol 5-phosphate 4-kinase type II alpha, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns(5)P-4-kinase isoform 2-alpha
배경	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha is a ~46 kDa protein. Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Has both ATP- and GTP-dependent kinase activities. May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. Required for lysosome-peroxisome membrane contacts and intracellular cholesterol transport through modulating peroxisomal PtdIns(4,5)P2 level. 1. Davis, MI. et al. (2013) PloS one 8, e54127. PMID: 23326584 2. Rameh, LE. et al. (1997) Nature 390, 192-6. PMID: 9367159 3. Sumita, K. et al. (2016) Molecular cell 61, 187-98. PMID: 26774281 4. Wilcox, A. et al. (2008) FEBS letters 582, 1391-4. PMID: 18364242 5. Hu, A. et al. (2018) Journal of lipid research 59, 507-514. PMID: 29353240 6. Wang, DG. et al. (2019) Cell reports 27, 1991-2001.e5. PMID: 31091439
참고사항	For research use only

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Human PIP4K2A Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human PIP4K2A Recombinant Protein (N-His) (HD637012)

개요

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