Human PIP4P1 Recombinant Protein (N-His) (HC748012)

Name: Human PIP4P1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC748012
Price: 211 USD
Availability: InStock

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개요

카탈로그 번호	HC748012
설명	Recombinant Human PIP4P1 Protein, N-His (HC748012) expressed in E. coli, spanning Met81-Arg211. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q86T03
단백질 길이	Met81-Arg211
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	16.96 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	C14orf9, EC:3.1.3.78, PIP4P1, PtdIns-4,5-P2 4-Ptase I, TMEM55B, Transmembrane protein 55B, Type 1 PtdIns-4,5-P2 4-Ptase, Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
배경	Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase is a ~29 kDa protein. Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. Regulates lysosomal positioning by recruiting JIP4 to lysosomal membranes, thus inducing retrograde transport of lysosomes along microtubules. Contributes to assembly of the V-ATPase complex in lipid rafts of the lysosomal membrane and to subsequent amino acid-dependent activation of mTORC1. May play a role in the regulation of cellular cholesterol metabolism. 1. Ungewickell, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 18854-9. PMID: 16365287 2. Willett, R. et al. (2017) Nature communications 8, 1580. PMID: 29146937 3. Hashimoto, Y. et al. (2018) Genes to cells : devoted to molecular & cellular mechanisms 23, 418-434. PMID: 29644770 4. Medina, MW. et al. (2014) Arteriosclerosis, thrombosis, and vascular biology 34, 1917-23. PMID: 25035345
참고사항	For research use only

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Human PIP4P1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human PIP4P1 Recombinant Protein (N-His) (HC748012)

개요

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