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| 카탈로그 번호 | HD886012 |
|---|---|
| 설명 |
Recombinant Human POGLUT2 Protein, N-His (HD886012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q6UW63 |
| 단백질 길이 | Ser32-Val468 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | EC:2.4.1.-, EC:2.4.2.-, EP58, ER protein 58, ERp58, Endoplasmic reticulum resident protein 58, KDEL motif-containing protein 1, KDELC1, POGLUT2, Protein O-glucosyltransferase 2, Protein O-xylosyltransferase POGLUT2 |
| 배경 | Protein O-glucosyltransferase 2 is a ~58 kDa protein. Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway. 1. Takeuchi, H. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E8395-E8402. PMID: 30127001 2. Williamson, DB. et al. (2021) The Journal of biological chemistry 297, 101055. PMID: 34411563 |
| 참고사항 | For research use only |
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