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| 카탈로그 번호 | HD034012 |
|---|---|
| 설명 |
Recombinant Human RANBP1 Protein, N-His (HD034012) expressed in E. coli, spanning Asp44-Gln201. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P43487 |
| 단백질 길이 | Asp44-Gln201 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 20.74 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | RANBP1, Ran-binding protein 1, Ran-specific GTPase-activating protein, RanBP1 |
| 배경 | Ran-specific GTPase-activating protein is a ~23 kDa protein. Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L. 1. Koyama, M. et al. (2010) The EMBO journal 29, 2002-13. PMID: 20485264 2. Li, HY. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1886-95. PMID: 17671426 3. Bischoff, FR. et al. (1995) The EMBO journal 14, 705-15. PMID: 7882974 4. Hayashi, N. et al. (1995) Molecular & general genetics : MGG 247, 661-9. PMID: 7616957 |
| 참고사항 | For research use only |
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