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| 카탈로그 번호 | HC868012 |
|---|---|
| 설명 |
Recombinant Human RBM47 Protein, N-His (HC868012) expressed in E. coli, spanning Asn31-Gly334. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | A0AV96 |
| 단백질 길이 | Asn31-Gly334 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 36.94 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | RBM47, RNA-binding motif protein 47, RNA-binding protein 47 |
| 배경 | RNA-binding protein 47 is a ~64 kDa protein. Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. 1. Guan, R. et al. (2013) Developmental dynamics : an official publication of the American Association of Anatomists 242, 1395-404. PMID: 24038582 2. Fossat, N. et al. (2014) EMBO reports 15, 903-10. PMID: 24916387 3. Cieply, B. et al. (2016) Cell reports 15, 247-55. PMID: 27050523 4. Wolfe, AD. et al. (2019) Journal of molecular biology 431, 1506-1517. PMID: 30844405 5. Kim, YE. et al. (2019) Oncogene 38, 6521-6536. PMID: 31358901 6. Wang, K. et al. (2021) EMBO reports 22, e52205. PMID: 34160127 |
| 참고사항 | For research use only |
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