

| 카탈로그 번호 | HS734022 |
|---|---|
| 설명 |
Recombinant Human SLC1A5 Protein, N-GST & C-His (HS734022) expressed in E. coli, spanning Gln154-Asn230. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q15758 |
| 단백질 길이 | Gln154-Asn230 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 36.18 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ASCT2, ATB(0), Baboon M7 virus receptor, M7V1, Neutral amino acid transporter B(0), RD114/simian type D retrovirus receptor, RDR, RDRC, SLC1A5, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5 |
| 배경 | Neutral amino acid transporter B(0) is a ~56 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation. Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way. Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation. 1. Dun, Y. et al. (2007) Experimental eye research 84, 191-9. PMID: 17094966 2. Pingitore, P. et al. (2013) Biochimica et biophysica acta 1828, 2238-46. PMID: 23756778 3. Scalise, M. et al. (2015) FEBS letters 589, 3617-23. PMID: 26492990 4. Garaeva, AA. et al. (2018) Nature structural & molecular biology 25, 515-521. PMID: 29872227 5. Mazza, T. et al. (2021) FEBS letters 595, 3030-3041. PMID: 34741534 6. Kekuda, R. et al. (1996) The Journal of biological chemistry 271, 18657-61. PMID: 8702519 7. Borowska, AM. et al. (2024) Nature communications 15, 6570. PMID: 39095408 8. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177 9. Oburoglu, L. et al. (2014) Cell stem cell 15, 169-84. PMID: 24953180 |
| 참고사항 | For research use only |
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