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| 카탈로그 번호 | HD384012 |
|---|---|
| 설명 |
Recombinant Human SLC5A6 Protein, N-His-KSI (HD384012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9Y289 |
| 단백질 길이 | Tyr122-Thr140&Asn274-Ser293&Ala317-Pro352&Gly550-Leu636 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 34.35 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Na(+)-dependent multivitamin transporter, SLC5A6, SMVT, Sodium-dependent multivitamin transporter, Solute carrier family 5 member 6, hSMVT |
| 배경 | Sodium-dependent multivitamin transporter is a ~68 kDa protein. Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide. Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+):substrate is 2:1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake. Required for biotin and pantothenate uptake in the intestine across the brush border membrane. Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin. Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier. 1. Wang, H. et al. (1999) The Journal of biological chemistry 274, 14875-83. PMID: 10329687 2. Balamurugan, K. et al. (2005) American journal of physiology. Renal physiology 288, F823-31. PMID: 15561972 3. Subramanian, VS. et al. (2009) American journal of physiology. Cell physiology 296, C663-71. PMID: 19211916 4. de Carvalho, FD. et al. (2011) The Journal of biological chemistry 286, 131-7. PMID: 20980265 5. Ghosal, A. et al. (2011) Biochimica et biophysica acta 1808, 2073-80. PMID: 21570947 6. Ghosal, A. et al. (2012) Biochimica et biophysica acta 1818, 97-102. PMID: 22015582 7. Uchida, Y. et al. (2015) Journal of neurochemistry 134, 97-112. PMID: 25809983 8. Zehnpfennig, B. et al. (2015) The Journal of biological chemistry 290, 16372-82. PMID: 25971966 9. Subramanian, VS. et al. (2017) Human genetics 136, 253-261. PMID: 27904971 10. Lakhan, R. et al. (2017) American journal of physiology. Cell physiology 312, C376-C384. PMID: 28052864 |
| 참고사항 | For research use only |
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