Human SLCO2A1 Recombinant Protein (N-His) (HP622022)

Name: Human SLCO2A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP622022
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요
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개요

카탈로그 번호	HP622022
설명	Recombinant Human SLCO2A1 Protein, N-His (HP622022) expressed in E. coli, spanning Phe416-Ala518. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q92959
단백질 길이	Phe416-Ala518
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	12.97 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	OATP2A1, PGT, PHOAR2, Prostaglandin transporter, SLC21A2, SLCO2A1, Solute carrier family 21 member 2, Solute carrier organic anion transporter family member 2A1
배경	Solute carrier organic anion transporter family member 2A1 is a ~70 kDa protein. Mediates the transport of prostaglandins (PGs, mainly PGE2, PGE1, PGE3, PGF2alpha, PGD2, PGH2) and thromboxanes (thromboxane B2) across the cell membrane. PGs and thromboxanes play fundamental roles in diverse functions such as intraocular pressure, gastric acid secretion, renal salt and water transport, vascular tone, and fever. Plays a role in the clearance of PGs from the circulation through cellular uptake, which allows cytoplasmic oxidation and PG signal termination. PG uptake is dependent upon membrane potential and involves exchange of a monovalent anionic substrate (PGs exist physiologically as an anionic monovalent form) with a stoichiometry of 1:1 for divalent anions or of 1:2 for monovalent anions. Uses lactate, generated by glycolysis, as a counter-substrate to mediate PGE2 influx and efflux. 1. Chan, BS. et al. (2002) American journal of physiology. Renal physiology 282, F1097-102. PMID: 11997326 2. Gose, T. et al. (2016) Prostaglandins & other lipid mediators 122, 10-7. PMID: 26692285 3. Lu, R. et al. (1996) The Journal of clinical investigation 98, 1142-9. PMID: 8787677 4. Nomura, T. et al. (2004) Molecular pharmacology 65, 973-8. PMID: 15044627 5. Nakanishi, T. et al. (2017) The AAPS journal 20, 13. PMID: 29204966 6. Kang, J. et al. (2006) Human reproduction (Oxford, England) 21, 592-9. PMID: 16339169
참고사항	For research use only

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Human SLCO2A1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human SLCO2A1 Recombinant Protein (N-His) (HP622022)

개요

이미지

참고 문헌

데이터시트

SDS

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