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| 카탈로그 번호 | HD371012 |
|---|---|
| 설명 |
Recombinant Human TAF2 Protein, N-His (HD371012) expressed in E. coli, spanning Tyr26-Gly527. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q6P1X5 |
| 단백질 길이 | Tyr26-Gly527 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 59.75 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | 150 kDa cofactor of initiator function, CIF150, RNA polymerase II TBP-associated factor subunit B, TAF(II)150, TAF2, TAF2B, TAFII-150, TAFII150, TBP-associated factor 150 kDa, Transcription initiation factor TFIID 150 kDa subunit, Transcription initiation factor TFIID subunit 2 |
| 배경 | Transcription initiation factor TFIID subunit 2 is a ~136 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF2 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF1. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Kaufmann, J. et al. (1998) Molecular and cellular biology 18, 233-9. PMID: 9418870 3. Martinez, E. et al. (1998) Molecular and cellular biology 18, 6571-83. PMID: 9774672 |
| 참고사항 | For research use only |
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