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Human TRAF7 Recombinant Protein (N-His) (HD350012)

Human TRAF7 Recombinant Protein (N-His)
Human TRAF7 Recombinant Protein (N-His)
가격(USD):
사양:
  • 50ug
  • 100ug
  • 1mg
수량:
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  • 개요

  • 이미지

  • 참고 문헌

  • 데이터시트

  • SDS

개요
카탈로그 번호HD350012
설명
Recombinant Human TRAF7 Protein, N-His (HD350012) expressed in E. coli, spanning Ile385-Cys670. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템E. coli
등록번호Q6Q0C0
단백질 길이Ile385-Cys670
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Homo sapiens (Human)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
예측 분자량 33.95 kDa
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름E3 ubiquitin-protein ligase TRAF7, EC:2.3.2.-, EC:2.3.2.27, RFWD1, RING finger and WD repeat-containing protein 1, RING finger protein 119, RING-type E3 ubiquitin transferase TRAF7, RNF119, TNF receptor-associated factor 7, TRAF7
배경

E3 ubiquitin-protein ligase TRAF7 is a ~74 kDa protein. E3 ubiquitin and SUMO-protein ligase that plays a role in different biological processes such as innate immunity, inflammation or apoptosis. Potentiates MAP3K3-mediated activation of JUN/AP1 and DDIT3 transcriptional regulators. Negatively regulates MYB transcriptional activity by sequestering it to the cytosol via SUMOylation. Plays a role in the phosphorylation of MAPK1 and/or MAPK3, probably via its interaction with MAP3K3. Negatively regulates RLR-mediated innate immunity by promoting 'Lys-48'-linked ubiquitination of TBK1 through its RING domain to inhibit the cellular antiviral response.

1. Xu, LG. et al. (2004) The Journal of biological chemistry 279, 17278-82. PMID: 15001576
2. Huang, JP. et al. (2023) Virologica Sinica 38, 419-428. PMID: 37086853
3. Bouwmeester, T. et al. (2004) Nature cell biology 6, 97-105. PMID: 14743216
4. Zotti, T. et al. (2011) The Journal of biological chemistry 286, 22924-33. PMID: 21518757
참고사항 For research use only
이미지
  • Human TRAF7 Recombinant Protein (N-His)

    SDS-PAGE

    SDS-PAGE for Human TRAF7 Recombinant Protein (N-His)

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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