

| 카탈로그 번호 | HD082012 |
|---|---|
| 설명 |
Recombinant Human VSX2 Protein, N-His-KSI (HD082012) expressed in E. coli, spanning Thr2-Ala361. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P58304 |
| 단백질 길이 | Thr2-Ala361 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 55.04 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CHX10, Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, VSX2, Visual system homeobox 2 |
| 배경 | Visual system homeobox 2 is a ~39 kDa protein. Acts as a transcriptional regulator through binding to DNA at the consensus sequence 5'-[TC]TAATT[AG][AG]-3' upstream of gene promoters. Plays a significant role in the specification and morphogenesis of the sensory retina. May play a role in specification of V2a interneurons during spinal cord development. Mediates differentiation of V2a interneurons by repression of motor neuron gene transcription, via competitively binding to response elements that are activated by the ISL1-LHX3 complex, such as VSX1. Acts as a positive transcriptional regulator of NXNL1; regulation is significantly increased in synergy with VSX1. 1. Capowski, EE. et al. (2016) Stem cells (Dayton, Ohio) 34, 2625-2634. PMID: 27301076 2. Clark, AM. et al. (2008) Brain research 1192, 99-113. PMID: 17919464 3. Clovis, YM. et al. (2016) Cell reports 16, 1642-1652. PMID: 27477290 4. Dorval, KM. et al. (2006) The Journal of biological chemistry 281, 744-51. PMID: 16236706 |
| 참고사항 | For research use only |
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