Human ZFP36L1 Recombinant Protein (N-GST & C-His) (HC370022)

Name: Human ZFP36L1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC370022
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	HC370022
설명	Recombinant Human ZFP36L1 Protein, N-GST & C-His (HC370022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q07352
단백질 길이	Arg121-Arg195
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	BERG36, BRF1, Butyrate response factor 1, EGF-response factor 1, ERF-1, ERF1, RNF162B, TIS11B, TPA-induced sequence 11b, ZFP36-like 1, ZFP36L1, Zinc finger protein 36, C3H1 type-like 1, mRNA decay activator protein ZFP36L1
배경	mRNA decay activator protein ZFP36L1 is a ~36 kDa protein. Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Also induces the degradation of ARE-containing mRNAs even in absence of poly(A) tail. Binds to 3'-UTR ARE of numerous mRNAs. 1. Stoecklin, G. et al. (2002) The EMBO journal 21, 4709-18. PMID: 12198173 2. Ciais, D. et al. (2004) Oncogene 23, 8673-80. PMID: 15467755 3. Schmidlin, M. et al. (2004) The EMBO journal 23, 4760-9. PMID: 15538381 4. Benjamin, D. et al. (2006) Molecular and cellular biology 26, 9497-507. PMID: 17030608 5. Duan, H. et al. (2009) Molecular endocrinology (Baltimore, Md.) 23, 497-509. PMID: 19179481 6. Vignudelli, T. et al. (2010) Molecular biology of the cell 21, 3340-51. PMID: 20702587 7. Viengchareun, S. et al. (2014) Journal of the American Society of Nephrology : JASN 25, 2213-21. PMID: 24700863 8. Zekavati, A. et al. (2014) PloS one 9, e102625. PMID: 25014217 9. Adachi, S. et al. (2014) Nucleic acids research 42, 10037-49. PMID: 25106868 10. Chen, MT. et al. (2015) Scientific reports 5, 16229. PMID: 26542173
참고사항	For research use only

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Human ZFP36L1 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

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어세이 키트

Human ZFP36L1 Recombinant Protein (N-GST & C-His) (HC370022)

개요

이미지

참고 문헌

데이터시트

SDS

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