

| 카탈로그 번호 | MV344021 |
|---|---|
| 설명 |
Recombinant Mouse ANGPTL4 Protein, C-Fc (MV344021) expressed in Mammalian Cells, spanning Lys167-Ser410. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | Mammalian cells |
| 등록번호 | Q9Z1P8 |
| 단백질 길이 | Lys167-Ser410 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 55.79 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ANGPTL4, ANGPTL4 C-terminal chain, ANGPTL4 N-terminal chain, ARP4, Angiopoietin-like protein 4, Angiopoietin-related protein 4, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR |
| 배경 | Angiopoietin-related protein 4 is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis (Probable). 1. Xu, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 6086-91. PMID: 15837923 2. Desai, U. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11766-71. PMID: 17609370 3. Gusarova, V. et al. (2018) Nature communications 9, 2252. PMID: 29899519 4. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458 5. Galaup, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 18721-6. PMID: 17130448 6. Perdiguero, EG. et al. (2011) The Journal of biological chemistry 286, 36841-51. PMID: 21832056 |
| 참고사항 | For research use only |
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