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| 카탈로그 번호 | MX155012 |
|---|---|
| 설명 |
Recombinant Mouse CCL7/MCP-3 Protein, N-GST & C-His (MX155012) expressed in E. coli, spanning Lys40-Pro97. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q03366 |
| 단백질 길이 | Lys40-Pro97 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 34.97 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | C-C motif chemokine 7, CCL7, MCP-3, MCP3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7 |
| 배경 | C-C motif chemokine 7 is a ~10 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair. 1. Xu, H. et al. (2025) International immunopharmacology 147, 114027. PMID: 39805173 2. Tsou, CL. et al. (2007) The Journal of clinical investigation 117, 902-9. PMID: 17364026 3. Zhu, LP. et al. (2023) Molecular pain 19, 17448069231169373. PMID: 36998150 4. Ford, J. et al. (2018) Frontiers in immunology 9, 3063. PMID: 30671055 |
| 참고사항 | For research use only |
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