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Mouse CD9 Recombinant Protein (C-Fc) (MB984011)

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  • 50ug
  • 100ug
  • 1mg
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  • 개요

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개요
카탈로그 번호MB984011
설명
Recombinant Mouse CD9 Protein, C-Fc (MB984011) expressed in Mammalian Cells, spanning Thr110-Ile193. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템Mammalian cells
등록번호P40240
단백질 길이Thr110-Ile193
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Mus musculus (Mouse)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
예측 분자량 38.11 kDa
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름5H9 antigen, CD9, CD9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, MIC3, MRP-1, Motility-related protein, TSPAN29, Tetraspanin-29, Tspan-29, p24
배경

CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption.

1. Le Naour, F. et al. (2000) Science (New York, N.Y.) 287, 319-21. PMID: 10634790
2. Miyado, K. et al. (2000) Science (New York, N.Y.) 287, 321-4. PMID: 10634791
3. Kaji, K. et al. (2000) Nature genetics 24, 279-82. PMID: 10700183
4. Ishibashi, T. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 96-102. PMID: 14715942
5. Jégou, A. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10946-51. PMID: 21690351
6. Charrin, S. et al. (2013) Nature communications 4, 1674. PMID: 23575678
7. Takeda, Y. et al. (2003) The Journal of cell biology 161, 945-56. PMID: 12796480
9. Takeda, Y. et al. (2008) The Journal of biological chemistry 283, 26089-97. PMID: 18662991
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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