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| 카탈로그 번호 | MC475022 |
|---|---|
| 설명 |
Recombinant Mouse CD91/LRP1 Protein, N-His (MC475022) expressed in E. coli, spanning Lys521-Phe978. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q91ZX7 |
| 단백질 길이 | Lys521-Phe978 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 53.76 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, CD91, LRP-1, LRP-515, LRP-85, LRP1, LRPICD, Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Prolow-density lipoprotein receptor-related protein 1 |
| 배경 | Prolow-density lipoprotein receptor-related protein 1 is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an alpha-2-macroglobulin receptor. 1. Herz, J. et al. (1992) Cell 71, 411-21. PMID: 1423604 2. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178 |
| 참고사항 | For research use only |
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